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Molecular pathology of age-related macular degeneration

Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the world. Although the etiology and pathogenesis of AMD remain largely unclear, a complex interaction of genetic and environmental factors is thought to exist. AMD pathology is characterized by degeneration involving the retinal photoreceptors, retinal pigment epithelium, and Bruch’s membrane, as well as, in some cases, alterations in choroidal capillaries. Recent research on the genetic and molecular underpinnings of AMD brings to light several basic molecular pathways and pathophysiological processes that might mediate AMD risk, progression, and/or response to therapy.

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dave's picture

THE ROLE OF THE IMMUNE SYSTEM IN OPTIC NERVE REGENERATION

THE ROLE OF MACROPHAGES IN OPTIC NERVE REGENERATION

Neuroscience. 2009 February 6; 158(3): 1039–1048.

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dave's picture

Turmeric root is good for the retina

I eat the spice turmeric almost every day. My favorite way to consume it is to use the fresh root in my cooking. If I do not have fresh turmeric root available, I'll use organic turmeric root powder and mix it in with my food (or even sprinkle a little on top if I'm not cooking). turmeric for healthy eyes

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Botanical lipids, inflammatory disorders, glaucoma

Read the abstract or download the article here...

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Glaucoma, Inflammation and Oxidative Stress: An Attempt to Unify Recent News

This article is my attempt to unify some of what has been proposed about the mechanism underlying retinal ganglion cell (RGC) loss in glaucoma. I am going to quickly dive right into the biochemical details of the process as I understand it, and then I will conclude this article with supplementary material meant to familiarize readers with many of the technical terms. Some of you may want to read this supplementary material first if you are not familar with things like glial cells. (And please ask for further clarifications in the comments to this article.)

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