The Effect of Travoprost Z, Latanoprost and Their Individual Components on the Ocular Surface (Corneal and Conjunctival Epitheli

 Prostaglandin analogues (PGAs) are the most common treatment for glaucoma. Most PGA formulations, like travoprost and latanoprost, contain the preservative benzalkonium chloride (BAK). Travoprost Z is preserved with a new ionic buffered preservative system, sofZia. To evaluate the potential toxicity of travoprost Z, travoprost, latanoprost and their components to the ocular surface, a tissue culture model utilizing immortalized corneal and conjunctival epithelial cells was utilized.