cortisol, its metabolites and glaucoma

I am slowly going through the hormones and glaucoma connection.
This is, I suspect, related to stress, malnutrition and intoxification.
But the main point is that finally the body is hit not only through raised cortisol (stress initially) but also malfunctioning liver and other tissues where cortisol is being metabolised, so that improper ratio of cortisol metabolites (even when on the surface cortisol level are fine) are further disrupting homeostasis.
This research paper had a "knockout" effect on me, especially given that I know that I fullfill probably the criteria for overexpression of 11betaHSD1.

Inhibition of 11b-hydroxysteroid dehydrogenase type 1 lowers intraocular pressure in patients with ocular hypertension