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dave's picture

FDA says Allergan eyelash drug promotion is misleading-it's about time!

Allergan's Latisse is a repackaged version of its Lumigan glaucoma drug. Many of us taking glaucoma eye drops would love to be able to stop using them due to the side effects. I find it disturbing that Allergan hopes to earn $500 million per year in revenue from selling this glaucoma drug as a means to lengthen eye lashes for cosmetic purposes. Sure, there are some individuals who have a genuine need for such a medication, but in order to reach their $500 million sales target, Allergan is going to have to sell a lot of this drug to average people without a genuine medicine need for it. And the following story underscores that point.

dave's picture

New prostaglandin derivative for glaucoma treatment

A hydrogen sulphide-releasing derivative of latanoprost acid (ACS 67) was synthesized and tested in vivo to evaluate its activity on reduction of intraocular pressure and tolerability. Glutathione (GSH) and cGMP content were also measured in the aqueous humour. The increased reduction of intraocular pressure, with a marked increase of GSH and cGMP and the related potential neuroprotective properties, make this compound interesting for the treatment of glaucoma. This is the first time that an application of a hydrogen sulphide-releasing molecule is reported for the treatment of ocular diseases.

Elena Perrino a, Caterina Uliva b, Cecilia Lanzi b, Piero Del Soldato c, Emanuela Masini b, Anna Sparatore a

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dave's picture

An Improved Technique for Glaucoma Eye Drop Administration

Correct instillation of eye drops is crucial for successful treatment of eye disease. Many patients have difficulties instilling eye drops, especially patients with loss of fixation, who cannot see the tip of the bottle. These patients may turn to harmful techniques, such as touching the dropper tip to the eye, or wasteful ones, such as feeling the sensation of drops hitting the eye or lower lid.1 Non-compliance may become an issue as well, resulting from a combination of poor drop administration and frustration. The frustration stems from an inability to see the bottle tip.

We describe a new method of drop instillation which increases the accuracy with which eye drops are dispensed, thereby decreasing the incidence of harmful techniques, and possibly increasing compliance.

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jarek's picture

Applying eyedrops my way

Hello to everyone with my first post. I'd like to pass big thanks to the founder(s) and maintainter(s) of this site (by the way: page lacks kind of "who we are" link). I'm happy to join your community. I hope I'll be able to give it as much as I can take from it.

I'm on low but frequent doses of pilocarpine for a few months. This drops show their effect in about 30 minutes, so it's easy to tell if they are working. So finding a way to make them work always wasn't very difficult.

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Which is the eye drop with less side effects?

 Hi again.. i'm happy to had found a place where i can discuss of intraocular hypertension..even if is in english.. and i'm italian!..

i would want to ask you which is the eye drop - for intraouclar pression elevated (mine is24)  with less side effects.. pilocarpine? travatan? or timogel? or there are other bettar with less side effects? anyone of you tried something else?

thanks for your help

Smile

 

Sandro

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