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Prog Retin Eye Res (2009) 0

By MC Grieshaber, J Flammer

Fluctuations in IOP have been pinpointed as a potential cause for glaucoma and a factor in worsening the eye damage caused by the disease, writes Joseph Caprioli, M.D., of the Jules Stein Eye Institute, UCLA, in an accompanying editorial.

Why should IOP fluctuation be damaging? Theories abound about the mechanisms of retinal ganglion cell damage in glaucoma, but no single cellular or molecular cause satisfactorily explains the condition in all patients, Dr. Caprioli writes. Long-term variability may disrupt homeostatic mechanisms. Irregular and large IOP fluctuations may cause a loading and unloading of stresses, and as opposed to conditions of static stress, the tissue is unable to compensate and damage occurs.

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In addition to making quick circumstantial notes relavant to certain measurements in my IOP recording regimen, I have felt in the need for some 'snapshot' indicators of certain consciousness indicators to include in a separate field of my spreadsheet. These I plan on noting at the end of the day (and maybe at noon). I may also note them at other times (like pressures noticably above and below my baseline for that time period).

Hi. I am interested in self-tonometry. My interest in self-tonometry is derived from my understanding of variations in biometric measurements, from as simple as basic body temperature readings to as complex as using electromyography to study the cooperative activity of muscles in making speech sounds, my doctoral research area many years ago.

I have optic nerve damage and now im totally blind.  I am interested in volunteering in this experiment when you are able to test on humans.

The intraocular pressure is still a very important, of not the most important factor in glaucoma. This is because it is the only factor for which proof has been accumulated that it has a direct relationship with glaucomatous damage. In NPG the influence of the intraocular pressure alone is doubtful, but as an accessory risk factor deteriming the perfusion pressure it may very probably have some importance. The man intraocular pressure in a normal population varies between 15.1 mmHg and 16.5 mmHg (occasionallly 17.2 mmHg. The standard deviation varies from 2.5 mmHg to 3.8 mmHg...

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It has been a long time since I shared a recipe on FitEyes.com. My last recipe was Ayurvedic Pizza. Today I made cornbread for the first time in my adult life. As usual, I created my own recipe and gave it an Ayurvedic slant.

Ingredients:

Researchers at The Schepens Eye Research Institute, an affiliate of Harvard Medical School, have reported success transplanting stem cells into the diseased eye. More importantly, a percentage of these cells have actually taken on some of the characteristics of retinal cells and extended into the optic nerve.

Although in its infancy, stem cell research has tremendous potential for helping millions of people whose vision has been impaired by injuries and diseases including glaucoma.

Glaucoma is an eyesight ailment characterized by an increase of pressure of the fluid within the eyeball.  This increased pressure causes abnormal changes in the optic nerve and defects in the field of vision.

Thanks to God Lourdes Water reduce my ocular pression! [EDITOR: intraocular pressure]

Dave, I seem to have higher IOP on stressful days and weight lifting days.

An amazing website to promote life quality and life span.