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Lowering of intraocular pressure by wild carrot seed extract in rabbits

Submitted by dave on Fri, 06/19/2009 - 7:53am

In normotensive rabbits topical application of Daucus carota seed extract at the concentration of 0.3, 0.6 and 1.2% resulted in mean IOP reduction of 19.33. 23.20 and 25.61% respectively from baseline.

As no significant difference was observed between the change in IOP in 0.6 and 1.2% extract treated groups, 0.6% concentration was chosen for further evaluation in rabbits with experimentally elevated IOP.

Fast food hamburgers: what are we really eating?

Submitted by dave on Fri, 06/05/2009 - 10:17am

Americans consume about 5 billion hamburgers a year. It is presumed that most hamburgers are Abstract composed primarily of meat. The purpose of this study is to assess the content of 8 fast food hamburger brands using histologic methods. Eight different brands of hamburgers were evaluated for water content by weight and microscopically for recognizable tissue types.

Glial fibrillary acidic protein (GFAP) staining was used to evaluate for brain tissue. Water content by weight ranged from 37.7% to 62.4% (mean, 49%).

Brain's Object Recognition System Activated By Touch Alone

Submitted by dave on Mon, 06/01/2009 - 10:17pm

Portions of the brain that activate when people view pictures of objects compared to scrambled images can also be activated by touch alone, confirms a new report published online on May 28th in Current Biology, a Cell Press publication.

"That's the nub of the paper," said Harriet Allen of the University of Birmingham. "Part of the brain is for object processing irrespective of the sensory input coming in."

Instructions for Sample Spreadsheets for Intraocular Pressure Records

Submitted by dave on Mon, 06/01/2009 - 12:30pm

There are two Excel spreadsheets available:

Both have the same column layout for the important data elements, and this is really the only important feature of any spreadsheet to me. The SimpleSample (Measurements tab) shows the key aspects.

Drink Coffee? Have Glaucoma or Elevated Eye Pressure? Read this.

Submitted by dave on Sun, 05/31/2009 - 7:46pm

Avisar R, Avisar E, Weinberger D: Effect of coffee consumption on IOP. Ann Pharmacother 2002;36:992-995.

BACKGROUND: Many ophthalmologists instruct patients with glaucoma to avoid coffee, although data supporting this practice are insufficient.

OBJECTIVE: To estimate the effect of drinking coffee on IOP.

The Comfort I Get From Monitoring My Eye Pressure

Submitted by dave on Sat, 05/30/2009 - 2:13pm

With the recent website upgrade to FitEyes.com, I decided to send an email to all registered member. While writing the email I was inspired to discuss more of my experiences with self-tonometry, the process of monitoring my own eye pressure. After I wrote and sent the email, I realized that we have a lot of visitors to FitEyes.com who are not registered and who would not be able to see the experiences and thoughts I shared with the registered members. Therefore, because I feel very passionate about the benefits of self-tonometry, I decided to post the entire email on my blog. Here it is (and now it is updated to reflect recent events such as my grandmother's most recent birthday).

Hi Everyone - I just upgraded the FitEyes.com website. It has been a long, long time since I have sent an email to all members. FitEyes has continued to grow and flourish in recent months. I want to take this opportunity to invite you to visit the new website and let me know what you think. Not only will you see a new design and new features, you will find lots of new content (some of it potentially controversial).

New Website Features

You will see that FitEyes.com has many new features. It is running on open source software now. (For you techies, the operating system is open source too: Ubuntu Linux.) You can form friendships and communicate privately with other FitEyes members. There are lots of other new features, so please explore and try them out.

Self-Monitoring Eye Pressure

It is my strong belief that almost every glaucoma patient or glaucoma suspect (or anyone with elevated intraocular pressure) will benefit greatly from self-tonometry. The practice of frequently monitoring your own eye pressure in your daily life will be universal in the future -- just as monitoring blood sugar is a normal part of managing diabetes today.

Meeting To Discuss Non-medical Management of Eye Pressure and Self-Tonometry

Submitted by dave on Sat, 05/30/2009 - 1:59pm

This year the World Glaucoma Congress (WGC) is taking place in the United States (Boston, MA) from July 8th to 11th. Dr. Ritch will be there, as will Marcel and I.

I believe all of you know, or know of, Dr. Ritch. Marcel is a key founder of the International Society for Self-Tonometry (ISST), of which Dr. Ritch is Honorary Chairman. Marcel is a driving force behind getting me and several other self-tonometrists together in Boston.

No disease in the brain of a 115-year-old woman

Submitted by dave on Fri, 05/29/2009 - 3:28pm

Are there limits to the duration of high quality of life? Are there limits to healthy life for a human brain? [These questions are relevalant for vision as well as cognitive health because the optic nerve is part of the central nervous system.]

Molecular pathology of age-related macular degeneration

Submitted by dave on Fri, 05/29/2009 - 11:20am

Age-related macular degeneration (AMD) is a leading cause of irreversible blindness in the world. Although the etiology and pathogenesis of AMD remain largely unclear, a complex interaction of genetic and environmental factors is thought to exist. AMD pathology is characterized by degeneration involving the retinal photoreceptors, retinal pigment epithelium, and Bruch’s membrane, as well as, in some cases, alterations in choroidal capillaries.

Open-Angle Glaucoma and the Risk of Stroke Development

Submitted by dave on Fri, 05/29/2009 - 10:45am

Open-Angle Glaucoma and the Risk of Stroke Development:  A 5-Year Population-Based Follow-Up Study

Background and Purpose—Although open-angle glaucoma (OAG) is associated with some of the risk factors of stroke development, there is still no published study addressing whether Open-Angle Glaucoma increases the risk of stroke development. We investigated the risk of stroke development after a diagnosis of Open-Angle Glaucoma and our results are reported in this article.

Ischemic optic neuropathy research review

Submitted by dave on Wed, 05/27/2009 - 5:40pm

Ischemic optic neuropathy is one of the major causes of blindness or seriously impaired vision, yet there is disagreement as to its pathogenesis, clinical features and especially its management. This is because ischemic optic neuropathy is not one disease but a spectrum of several different types, each with its own etiology, pathogenesis, clinical features and management. They cannot be lumped together. Ischemic optic neuropathy is primarily of two types: anterior (AION) and posterior (PION), involving the optic nerve head (ONH) and the rest of the optic nerve respectively.

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New prostaglandin derivative for glaucoma treatment

Submitted by dave on Mon, 05/25/2009 - 4:35pm

A hydrogen sulphide-releasing derivative of latanoprost acid (ACS 67) was synthesized and tested in vivo to evaluate its activity on reduction of intraocular pressure and tolerability. Glutathione (GSH) and cGMP content were also measured in the aqueous humour. The increased reduction of intraocular pressure, with a marked increase of GSH and cGMP and the related potential neuroprotective properties, make this compound interesting for the treatment of glaucoma.

Simple way to reduce your glaucoma risk by 60 percent

Submitted by dave on Sun, 05/24/2009 - 4:48pm

Cut your glaucoma risk by 60 percent by eating one serving a month of kale and collard greens or two or more servings a week of carrots.

http://www.ivanhoe.com/channels/p_channelstory.cfm?storyid=21287

Wearing swimming goggles can elevate intraocular pressure

Submitted by dave on Sun, 05/24/2009 - 1:53pm

We list three studies below that show swim googles can elevate eye pressure. Thanks to FitEyes member "togburn" we have a product recommendation for swimmers. The recommendation comes by way of optometrist Michelle Solomon in Richmond, VA, USA. Dr. Solomon is recommending swim goggles like the Aqua Sphere Seal Swim Mask by Aqua Sphere.

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